"Chefs Paco Ruano and Luis González Rodriguez opened Alcalde in Guadalajara after working at some of the world’s top-ranked restaurants, including Noma and Mugaritz. Though they bring international sensibilities and techniques to their open kitchen, they’re committed to working primarily with hyper-local ingredients, most sourced from the state of Jalisco.Seasonal menus may be the norm these days, but many of Alcalde’s dishes are likely to be unfamiliar even to aficionados of Mexican cuisine, ensuring an especially memorable culinary experience."

"Like the torta ahogada , birri ais a culinary specialty in Guadalajara, served everywhere from street-food stalls to sit-down restaurants. To leave the Pearl of the West without sampling it would be a loss, as it offersa quintessential taste of the city. Though there are plenty of places in Guadalajara where you can order birria , Birriería las 9 Esquinas is a favorite for its spicy, slow-cooked meat stew, typically made with lamb or goat. Local lore has it that this restaurant was the first ever to serve the dish."

"Around 10,000 animal bones and skulls, cast from aluminum, line the whitewashed walls of Hueso, a restaurant named after the Spanish word for “bone.” Chef Alfonso Cadena sourced the bones, which include a whale spine and a puma skull, over the course of a nine-month trip all over Mexico , then turned to his brother, Ignacio Cadena of Cadena + Asociados Concept Design, to execute the macabre décor. Perhaps even more impressive than the restaurant’s interior, however, is its menu, which features produce, poultry, and seafood from Jalisco and beef from Cadena’s home state of Sonora. Can’t-miss dishes include the short rib with bone marrow, and the mussels with beef stock."

"A trendy restaurant that draws both local and international diners, i Latina offers funky décor, inventive cocktails, and eclectic cuisine with Mexican, Asian, and Mediterranean flavors. Opened in 1999, the restaurant was a pioneer of contemporary cuisine in Guadalajara. Snag a table on the terrace for a great view of the city."

"For comida típica (home-style food) inGuadalajara, you can't beat La Chata, an old-school, diner-style restaurant that’s been around since 1942. Generations-old recipes for enchiladas, flautas, and the platillo jalisciense (fried chicken and five sides) along with hefty portions and low prices keep locals lined up around the block. However, the line moves fast and the food comes out faster, so you won’t be waiting for long."

"Chef Darren Walsh has come a long way since the 2001 New York Times review in which food critic William Grimes wrote that his Manhattan restaurant, Papillon, served “two-star food in a no-star setting”—all the way, in fact, to Guadalajara.The Irish chef, who trained in France and headed restaurants in New York, brings all these cultural and culinary influences—and many more—to Lula Bistro, where his food and presentation finally achieve parity.Diners can look forward to a seasonal, modern European tasting menu, complete with French-meets-Mexican dishes like beef filet, duck confit, and octopus, as well as a sophisticated wine list with several Mexican vintages."

"The torta ahogada , or drowned sandwich, is a Mexican specialty that can only be authentically sampled inGuadalajara—the salt used to make the distinctively dense, crusty bread comes from the region. The sandwich is filled with meat (usually carnitas) and drenched in a spicy salsa but, because of its hearty toll, manages to soak up the sauce without getting soggy. For the best version, head to small chain Tortas Toño, which has eight locations across Jalisco."

"A recently opened beer garden, Casa Trapiche serves Cerveza Colima’s delicious craft brews in a beautiful white house with a spacious terrace. Gourmet takes on local classics like seafood tacos and esquites with chicarrón from chef Nico Mejía pair perfectly with the extensive beer selection."

"Founded in 2004, Cerveza Minerva is one ofMexico’s original—and biggest—independent craft breweries. Sample the spot’s regular brews along with a variety of special editions in its tasting room, where a glass wall offers views into the factory where the beer is produced. There’s also a full food menu to complement what’s on tap."

"Although the craft cocktail movement is relatively new toGuadalajara, Fat Charlie has quickly made a name for itself as a place to get a really decent drink—that is, if you can get in. The bar bills itself as a speakeasy and requires a password to enter; find it by scouring Fat Charlie’s social media accounts. Once inside, guests can look forward to a laid-back atmosphere and globally inspired cocktails that will make your password search worth the time."

"One ofGuadalajara’s hippest bars stocks an awesome collection of agave-based spirits, with a focus on mezcal. In fact, its full name, Pare de Sufrir Tome Mezcal, means “to end suffering,drink mezcal.” Although it’s tucked away on a quiet street in Colonia Americana, the bar bursts with bright murals, string lights, and the sound of live bands or DJs playing everything from cumbia to rockabilly. Owner Pedro Jiménez Gurría also runs a local nonprofit called Mezonte, which promotes small producers making agave-based spirits in the traditional style."