"Anyone who has driven through Calistoga over the last 70 years has likely clocked the hotel's neon sign advertising hot springs and mud baths. This midcentury landmark is fresh off a sassy makeover with offerings that channel its namesake doctor, like arrival prescriptions (essential-oil blends), an updated spa, and rooms that feel more Coachella Valley than Napa (retro mini fridges and pale-pink bathrobes). The new restaurant, House of Better, takes influence from restaurateur Trevor Logan's time in the Southwest, with dishes like roasted green chile flatbread from the wood-fired oven. There are also tasty alcohol-free herbal tonics in case you need an antidote to all the wine-tasting. The hotel skews young and relatively inexpensive, qualities that can be hard to come by in Napa."