"In a city with such a concentration of luxe hotels, none do it quite like this Grand Canal classic. Though the 15th-century palazzo—now a member of the Luxury Collection—has been open to guests since 1895, a 15-month, $200 million revamp in 2013 ensured that it’s no creaky museum piece. (Most modern extras are cleverly concealed.) But it’s the sheer grace of the place that makes it so appealing. Of course, it’s all inimitably exquisite, with rich Rubelli fabrics and priceless art; but this silky cocoon also manages to be utterly affable. Nothing is too much trouble, from the staff who serve cocktails from the martini trolley to chef Daniele Turco, who creates wonders with castraure—those special Venetian baby artichokes. A restorative facial in the spa? A spin in the Riva Aquariva boat? Full immersion in local food at the culinary school? Only if you can take your eyes off that watery spectacle outside: This is still one of the most beautiful hotels in one of the most beautiful, and most fragile, spots in the world." - Sarah James, Anne Hanley