"The Duomo was started in 1290. But it took three centuries, 33 architects, 152 sculptors, 68 painters, and 90 mosaic masters to complete. It's a masterpiece of Gothic architecture. There is no fee to enter the Duomo, but visitors should get there early during high season as it is a popular attraction. Once inside, look for the San Brizio Chapel. Within, Luca Signorelli's nudes became famous for the subject matter and the form. His breathtaking frescos are considered some of the most important works of the Renaissance. They inspired Michelangelo’s own Last Judgment for the Sistine Chapel." - Laura Itzkowitz, Arlene Gibbs